1) Agishi T, Kitano Y, Suzuki T, et al:Improvement of peripheral circulation by low density lipoprotein adsorption. ASAIO Trans 1989;35:349-51 2) Mii S, Mori A, Sakata H, et al:LDL apheresis for arteriosclerosis obliterans with occluded bypass graft:change in prostacyclin and effect on ischemic symptoms. Angiology 1998;49:175-80 3) Kobayashi S, Moriya H, Negishi K, et al:LDL-aphereis up-regulates VEGF and IGF-1 in patients with ischemic limb. J Clin Apher 2003;18:115-9 4) Kobayashi S, Moriya H, Maesato K, et al:LDL-apheresis improves peripheral arteial occlusive disease with an implication for anti-inflammatory effects. J Clin Apher 2005;20:239-43 5) Kobayashi S, Oka M, Moriya H, et al:LDL-apheresis reduces p-selectin, CRP and fibrinogen―Possible important implications for improving atherosclerosis. Ther Apher Dial 2006;10:219-23 6) Hara T, Kiyomoto H, Hitomi H, et al:Low-density lipoprotein apheresis for haemodialyis patients with peripheral arteial disease reduces reactive oxygen species production via suppression of NADPH oxidase gene expression in leucocytes. Nephrol Dial Transplant 2009;24:3818-25 7) Tamura K, Tsurumi-Ikeya Y, Wakui H, et al:Therapeutic potential of low-density lipoprotein apheresis in the management of peripheral artery disease in patients with chronic kidney disease. Ther Apher Dial 2013;17:185-92 8) Ohtake T, Mochida Y, Matsumi J, et al:Beneficial effect of endovascular therapy and low-density lipoprotein apheresis combined treatment in hemodialysis patients with critical limb ischemia due to below-knee arteial lesions. Ther Apher Dial 2016;20:661-7